MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANTICOAGULATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
INNs of HNFs
A
heparin sodium
B
calcium heparin
C
nadroparin calcium
D
dalteparin sodium
Explanation: 

Detailed explanation-1: -Treatment of deep vein thrombosis, pulmonary embolism, unstable angina pectoris and acute peripheral arterial occlusion.

Detailed explanation-2: -The calcium salt form of heparin. As a glycosaminoglycan anticoagulant, heparin calcium binds to antithrombin III to form a heparin-antithrombin III complex.

Detailed explanation-3: -The only statistically significant difference between the two heparins was a larger haematoma formation at heparin injection sites when calcium heparin was used. Otherwise sodium-and calcium-heparin are equal in effect and side effects provided they come from the same heparin source.

Detailed explanation-4: -Heparin has a chelating effect on all cations, which is more pronounced for iCa. Hence, we hypothesized that iCa levels will be artifactually low when measured from a heparinized blood sample vs. a non-heparinized blood sample.

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