MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANTICOAGULATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The purpose of AVKs is to thin the blood to avoid the formation of thrombus in certain risky situations and to dissolve a thrombus already formed following treatment with heparin.
A
TRUE
B
FAUX
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Medicines are the best way to stop a clot from forming. The 2 main medicines that are used to help prevent clots are heparin and enoxaparin (Lovenox). Some people call them blood thinners. These are shots that will be given to you usually in the belly.

Detailed explanation-2: -Heparin (HEP) prevents thrombus formation (TF) and thrombus growth (TG), by accelerating thrombin (THR) inhibition by antithrombin III (ATIII). Recent studies suggest that dermatan sulphate which catalyzes thrombin inhibition by heparin cofactor II (HCII), can inhibit TF and TG as effectively as HEP.

Detailed explanation-3: -Heparin prevents extension of the thrombus and has been shown to significantly reduce (but not eliminate) the incidence of fatal and nonfatal PE as well as recurrent thrombosis.

Detailed explanation-4: -This medicine is sometimes called a blood thinner, although it does not actually thin the blood. Heparin will not dissolve blood clots that have already formed, but it may prevent the clots from becoming larger and causing more serious problems.

There is 1 question to complete.