MRCP UK EXAMINATIONS

Detailed explanation-1: -EDTA most important advantage is that it does not distort blood cells, making it ideal for the most hematological tests. It is known to cause erroneous results of platelet counts by automated hematological analysers yielding low platelets counts.

Detailed explanation-2: -It’s a tube coated with spray-dried K2EDTA on its inner wall. EDTA acts as an anticoagulant, binding the calcium ions and interrupting the clotting of the blood sample. EDTA is used for most hematology procedures, assessing complete blood count, preparing EDTA plasma, whole blood collection and bone marrow specimens.

Detailed explanation-3: -The most common side effect of EDTA is burning at the IV site. Chelating agents can also have serious, even life-threatening side effects. One of the most serious side effects of EDTA is kidney damage and kidney failure.

Detailed explanation-4: -An EDTA test is used to assess the function of your kidneys through a series of blood tests. EDTA refers to the name of the substance that you will receive by injection. EDTA contains a small amount of radioactive material. This allows it to act as a tracer which will show the kidney function.

Detailed explanation-5: -Disadvantages: 1-Excessive con % of EDTA will cause shrinkage of RBCs and erroneous PCV, MCV, and MCHC Results. 2-EDTAinterferes with blood chemistry tests as follows falsely decreases alkaline phosphates by binding Mg++. 3-Decreases CO2 combining power of blood.