MRCP UK EXAMINATIONS

Detailed explanation-1: -Glucocorticoids increase bone resorption and reduce bone formation [2-4]. The risk of bone loss is most pronounced in the first few months of use, followed by slower but steady loss of bone with continued use [3].

Detailed explanation-2: -Bone fractures, particularly in the spine or hip, are the most serious complications of osteoporosis. Hip fractures often are caused by a fall and can result in disability and even an increased risk of death within the first year after the injury.

Detailed explanation-3: -Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the first cause in young people. Bone loss and increased rate of fractures occur early after the initiation of corticosteroid therapy, and are then related to dosage and treatment duration.