MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

OSTEOPOROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Doing active physical activity is one way to prevent osteoporosis, why?
A
Physical activity increases the process of absorption by osteoclasts
B
Physical activity reduces the process of absorption by osteoclasts
C
Physical activity increases the process of bone formation by osteoblasts
D
Physical activity decreases the process of bone formation by osteoblasts
Explanation: 

Detailed explanation-1: -Osteoporosis is a metabolic bone disease that, on a cellular level, results from osteoclastic bone resorption not compensated by osteoblastic bone formation. This causes bones to become weak and fragile, thus increasing the risk of fractures.

Detailed explanation-2: -Furthermore, loading activates a molecular response that inhibits sclerostin and allows the activation of Wnt signaling, thereby osteoblastogenesis and bone formation. Finally, exercise shifts the adipogenic-to-osteogenic balance toward the osteoblast formation [21].

There is 1 question to complete.