MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

OSTEOPOROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which cells cause bone resorption?
A
Osteoclasts
B
Osteoblasts
C
Estrogen
D
Insulin
Explanation: 

Detailed explanation-1: -Osteoclasts are multinucleated cells that are responsible for resorption of bone, and increased activity of these cells is associated with several common bone diseases, including postmenopausal osteoporosis.

Detailed explanation-2: -Osteoclasts are responsible for aged bone resorption and osteoblasts are responsible for new bone formation (Matsuoka et al., 2014). The resorption and formation is in stable at physiological conditions. However, when the balance is disturbed, bone architecture or function will be abnormal.

Detailed explanation-3: -Osteoclasts are cells of hematopoietic origin that are responsible for bone resorption.

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