MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

PSORIASIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A characteristic defect of atopic dermatitis that contributes to the pathophysiology is the alteration of the barrier?
A
Epidermal
B
cutis
C
Both
D
None of the above
Explanation: 

Detailed explanation-1: -The pathophysiology of atopic dermatitis is complex and multifactorial, involving elements of barrier dysfunction, alterations in cell mediated immune responses, IgE mediated hypersensitivity, and environmental factors.

Detailed explanation-2: -Atopic dermatitis can cause a very itchy rash. Atopic dermatitis most often occurs where the skin flexes-inside the elbows, behind the knees and in front of the neck. Atopic dermatitis (eczema) is a condition that causes dry, itchy and inflamed skin. It’s common in young children but can occur at any age.

Detailed explanation-3: -Another theory suggests that in some cases a defective epidermis causes an individual to be particularly sensitive to substances that cause an inflammatory response. The inflammation that results from eczema irritates patches of skin, causing them to itch. Regions of elevated, fluid-filled bumps may also develop.

There is 1 question to complete.