CLINICAL ENCOUNTERS
SYSTEMIC SCLEROSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Treatment of systemic sclerosis is different for each organ involved, and immunosuppressive therapy is used for severe organ inflammation.
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Explanation:
Detailed explanation-1: -These immunosuppressing drugs include methotrexate, cyclosporine, antithymocyte globulin, mycophenolate mofetil and cyclophosphamide.
Detailed explanation-2: -The most commonly involved part of the gastrointestinal tract in systemic scleroderma is the esophagus. In affected individuals, the esophagus is unable to contract efficiently (esophageal dismotility) to allow food to reach the stomach.
Detailed explanation-3: -Patients with diffuse scleroderma are often treated with immunosuppressive drugs (e.g. MMF) which can help to prevent major organ complications. However, people with limited scleroderma are not often treated with these drugs but can still develop serious internal organ complications.
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