MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

SYSTEMIC SCLEROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is an anti-inflammatory treatment for systemic scleroderma?
A
Calcium channel blockers
B
Corticosteroids
C
Immunosuppressive drugs
D
Vitality
E
Spa treatment
Explanation: 

Detailed explanation-1: -Prednisone is an immunosuppresant used for treatment of autoimmune disorders. It may decrease inflammation by reversing increased capillary permeability and suppressing inflammatory cell activity. Prednisone is inactive and must be metabolized to prednisolone. Metabolism may be impaired in patients with liver disease.

Detailed explanation-2: -Two drugs are currently FDA approved to treat lung scarring, or pulmonary fibrosis, that occurs as a result of scleroderma: nintedanib and tocilizumab.

There is 1 question to complete.