NEUROLOGY
CEREBELLAR SYNDROME
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A friend has taken a job in a neuroscience research lab, and is studying neurons in a freshwater snail. He has been told to calculate the equilibrium potential of K+. Which equation will he use and what other information will he need?
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Nernst equation; concentration of K+ inside and outside of the cell
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Nernst equation; concentration of K+ inside and outside of the cell and permeability of K+
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Goldman equation; concentration of K+ inside and outside of the cell
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Goldman equation; concentration of K+ inside and outside of the cell and permeability of K+
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Nernst equation; concentration of K+, Na+, and Cl-inside and outside of the cell
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Explanation:
Detailed explanation-1: -Moreover, K+ is a positively charged ion that has an intracellular concentration of 120 mM, an extracellular concentration of 4 mM, and an equilibrium potential of-90 mV; this means that K+ will be in electrochemical equilibrium when the cell is 90 mV lower than the extracellular environment.
Detailed explanation-2: -The Nernst equation describes the electrochemical equilibrium in terms of the reversal potential. The reversal potential of an ion is the membrane potential value at which there is no net flux. K+ is more concentrated inside and has a negative reversal potential of ∼ −80mV .
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