NEUROLOGY
CEREBELLAR SYNDROME
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Climbing fibers originate from what structure
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Ipsilateral Pontine Nuclei
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Contralateral Pontine Nuclei
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Ipsilateral Inferior Olive
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Contralateral Inferior Olive
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Explanation:
Detailed explanation-1: -Climbing fibers originate from the inferior olive and pass the cerebellar cortex to supply strong excitatory synapses to Purkinje cells and other inhibitory interneurons.
Detailed explanation-2: -The inferior olivary nucleus is the only source of climbing fibers to the Purkinje cells in the cerebellum and it projects to both the cortex and the deeper nuclei of the cerebellum.
Detailed explanation-3: -The inferior olive, which provides the climbing fibers to Purkinje cells in the cerebellar cortex, has been implicated in various functions, such as learning and timing of movements, and comparing intended with achieved movements.
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