MRCP UK EXAMINATIONS

NEUROLOGY

CEREBELLAR SYNDROME

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Most of the output from the cerebellum comes from
A
Purkinje cell axons
B
Axons of cells in the deep nuclei
C
Mossy fibers
D
Climbing fibers
Explanation: 

Detailed explanation-1: -There are 2 major parts to the cerebellum, the cerebellar deep nuclei and the cerebellar cortex. Output from the cerebellum originates solely in the deep nuclei, where almost all of the neurons of the cerebellum reside. The cerebellum is divided into three subdivisions by two fissures that travel mediolaterally.

Detailed explanation-2: -Inhibitory Purkinje cells, the only output neurons of the cerebellar cortex, and their postsynaptic target neurons in the cerebellar nuclei, fire action potentials at high, sustained frequencies, suggesting spike rate modulation as a possible code.

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