MRCP UK EXAMINATIONS

Detailed explanation-1: -Huntington’s disease (HD) is an inherited disorder that causes nerve cells (neurons) in parts of the brain to gradually break down and die. The disease attacks areas of the brain that help to control voluntary (intentional) movement, as well as other areas.

Detailed explanation-2: -Huntington’s disease is caused by a faulty gene. Cells in parts of the brain are very sensitive to the effects of the faulty gene. This makes them function poorly and eventually die. A parent with the Huntington’s disease gene has one good copy of the gene and one faulty copy.

Detailed explanation-3: -Huntington’s disease is characterized by rapid uncontrollable muscle movements such as tics or muscle jerks (choreiform movements or chorea). This disorder causes a loss of coordination and personality changes.

Detailed explanation-4: -Friedreich ataxia (FA) is a rare inherited disease that causes progressive damage to your nervous system and movement problems. Nerve fibers in your spinal cord and peripheral nerves degenerate, becoming thinner.