MRCP UK EXAMINATIONS

Detailed explanation-1: -The key requirement for a diagnosis of MS is evidence of damage to the central nervous system that is disseminated in time and space. This means showing that damage has occurred at different dates (Dissemination in time, or DIT) and to different parts (Dissemination in space, or DIS) of the central nervous system.

Detailed explanation-2: -McDonald criteria dissemination in space-UpToDate. Dissemination in space is defined as the development of lesions in distinct anatomic locations within the central nervous system, indicating a multifocal process.