MRCP UK EXAMINATIONS

NEUROLOGY

MULTIPLE SCLEROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is the most helpful study in the clinical investigation of MS?
A
MRI
B
Radiography
C
Visual evoked potentials
D
Lumbar puncture
Explanation: 

Detailed explanation-1: -Magnetic resonance imaging has become the single most useful test for the diagnosis of MS; MRI is sensitive to brain changes which are seen in MS. Classically, the MRI shows lesions in the white matter deep in the brain near the fluid spaces of the brain (the ventricles).

Detailed explanation-2: -T2 MRI sequences are used to highlight areas of demyelination, which happens when the outer layer of the neurons is damaged due to MS activity. T2 sequences can be used to count the total number of MS lesions, which look like bright white spots on T2 sequences, and can be called “hyperintense”.

Detailed explanation-3: -The brain, spinal cord and nerves, as well as muscles, ligaments, and tendons are seen much more clearly with MRI than with regular x-rays and CT; for this reason MRI is often used to image knee and shoulder injuries.

There is 1 question to complete.