NEUROLOGY
PARKINSON S DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Changes to levels of ____ and ____ have key roles in Parkinson’s disease.
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dopamine; acetylcholine
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serotonin; acetylcholine
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dopamine; melatonin
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dopamine; serotonin
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Explanation:
Detailed explanation-1: -Parkinson’s disease is characterised by an imbalance between acetylcholine and dopamine which probably results from the degeneration of a dopaminergic nigrostriatal pathway. A new hypothesis is proposed to explain the development of this imbalance.
Detailed explanation-2: -Studies have shown that symptoms of Parkinson’s develop in patients with an 80 percent or greater loss of dopamine-producing cells in the substantia nigra. Normally, dopamine operates in a delicate balance with other neurotransmitters to help coordinate the millions of nerve and muscle cells involved in movement.
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