NEUROLOGY
PARKINSON S DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Peripheral nervous system
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Basal ganglia
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Substantria nigra
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Frontal lobe
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Detailed explanation-1: -The substantia nigra is a critical brain region for the production of dopamine and this neurochemical affects many systems of the central nervous system ranging from movement control, cognitive executive functions, and emotional limbic activity.
Detailed explanation-2: -The dopamine neurons in the substantia nigra express high levels of a pigment called neuromelanin, which accounts for their dark color. These dopamine neurons, however, are found predominantly in the substantia nigra pars compacta.
Detailed explanation-3: -The small cluster of cells in the substantia nigra pars compacta (SNpc) release the neurotransmitter dopamine to neurons of the striatum which project to the basal ganglia. The basal ganglia is connected to the thalamus and motor cortex which imparts control over motor output.