MRCP UK EXAMINATIONS

Detailed explanation-1: -Patients with schizophrenia perform poorly on an array of tasks that depend on prefrontal cortical function, for example, Continuous Performance (attention), Stroop (cognitive inhibition), Wisconsin Card Sort (cognitive flexibility), Delayed Response (working memory) and N-Back (working memory) tasks.

Detailed explanation-2: -Brain imaging shows that people with schizophrenia have less gray matter volume, especially in the temporal and frontal lobes. These areas of the brain are important for thinking and judgment. What’s more, gray matter loss continues over time.

Detailed explanation-3: -Schizophrenia might also be characterized by low dopamine in the prefrontal cortex, but again the evidence is inconclusive. 11 Some studies have found that patients with schizophrenia have elevated levels of dopamine in this region, while others suggest that there are too few dopamine receptors.