MRCP UK EXAMINATIONS

NEUROLOGY

PARKINSON S DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The risk of developing schizophrenia ____ with genetic similarity.
A
increases
B
decreases
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Your chances are highest–50%–if you have an identical twin with the disorder. But some people with schizophrenia have no history of it in their family. Scientists think that in these cases, a gene may have changed and made the condition more likely.

Detailed explanation-2: -Among biological factors, genes play an important role. Twin studies have shown that genetic factors account for about 80 percent of an individual’s risk of developing schizophrenia.

Detailed explanation-3: -Genetics of schizophrenia Schizophrenia is a familial neuropsychiatric disorder, namely, there is an increased risk of schizophrenia in the relatives of probands than in the population at large. It is around 10% in first degree relatives. Twin, family, and adoption studies suggest a heritability of 70%–80%.

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