MRCP UK EXAMINATIONS

NEUROLOGY

PERIPHERAL NEUROPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Alpha Lipoic Acid supply methyl group to damaged nerve and facilitates Remyelination
A
FALSE
B
TRUE
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Several studies suggest alpha-lipoic acid helps lower blood sugar levels. Its ability to kill free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage.

Detailed explanation-2: -Alpha-lipoic acid (a-lipoic acid or ALA) is a powerful antioxidant cofactor synthesized in mitochondria that could help stimulate nerves and regenerate nerve fibers, thus preventing disease progression.

Detailed explanation-3: -Lipoic acid has not be found to repair nerve damage. However, it may slow the progression of further nerve damage by inhibiting the migration of inflammatory cytokines that damage nerves and by slowing cell death of nerves in the brain and spine.

Detailed explanation-4: -Studies also found that alpha-lipoic acid supplements can help with neuropathy–nerve damage–caused by diabetes or cancer treatment. They seem to reduce symptoms like pain, tingling, and prickling in the feet and legs.

There is 1 question to complete.