MRCP UK EXAMINATIONS

Detailed explanation-1: -Because alpha-lipoic acid is an unproven treatment, there is no established dose. However, studies have used between 600-1, 800 milligrams daily for diabetes and neuropathy; one review concluded that the evidence is convincing for the use of 600 milligrams daily for three weeks on symptoms of diabetic neuropathy.

Detailed explanation-2: -Intravenous (IV) ALA can improve neuropathy symptoms when administered for three weeks, but symptom improvement with oral ALA is not clinically significant.

Detailed explanation-3: -Several studies suggest alpha-lipoic acid helps lower blood sugar levels. Its ability to kill free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage.

Detailed explanation-4: -While ALA is considered safe, there are no guidelines directing its use. Most oral supplements are sold in capsule or tablet formulations ranging from 100 milligrams to 600 milligrams. A dose of 600 milligrams to 1, 200 milligrams daily appears the most common in studies.