MRCP UK EXAMINATIONS

Detailed explanation-1: -Homocysteine is an amino acid in the blood, and elevated levels have been linked to dementia, heart disease, stroke, and osteoporosis. The good news: Homocysteine can be lowered easily and inexpensively with a trio of B vitamins-B6, B12, and folic acid.

Detailed explanation-2: -Vitamin B-6 (pyridoxine) is important for normal brain development and for keeping the nervous system and immune system healthy. Food sources of vitamin B-6 include poultry, fish, potatoes, chickpeas, bananas and fortified cereals.

Detailed explanation-3: -It is known that serum homocysteine is regulated by Vitamin B12 and folic acid, and supplementation with these vitamins decreases serum homocysteine levels. It is also known that folate, Vitamin B12, Vitamin B6 and riboflavin are involved in the metabolism of an S-containing amino acid, homocysteine.

Detailed explanation-4: -Vitamin B6 (pyridoxine) is essential for the amino acid metabolism. Hence, vitamin B6 assures the metabolism of neurotransmitters (e.g., GABA and serotonin), which are indispensable for signal transmission in the nervous system, and is associated with the glutamate release.