MRCP UK EXAMINATIONS

Detailed explanation-1: -Acute inflammatory demyelinating polyneuropathy (AIDP) is an autoimmune process characterized by progressive areflexic weakness and mild sensory changes. Sensory symptoms often precede motor weakness. About 20% of patients end up with respiratory failure.

Detailed explanation-2: -Acute inflammatory demyelinating polyneuropathy (AIDP), also known as Guillain-Barré syndrome, is a prototypic neuromuscular disorder in which approximately 25% of patients develop respiratory failure.

Detailed explanation-3: -The cause of AIDP is unknown. It is possible that this syndrome is the result of an autoimmune disease, meaning the immune system may be attacking parts of the body’s own nervous system. It has been noted that approximately 50% of the cases of AIDP occur following a viral or bacterial infection.

Detailed explanation-4: -Acute inflammatory demyelinating polyneuropathy (AIDP) was the first to be recognized over a century ago and is the most common form of GBS. In AIDP, the immune attack is directed at peripheral nerve myelin with secondary by-stander axon loss.

Detailed explanation-5: -Often AIDP symptoms are preceded by upper respiratory symptoms, diarrhea, vaccination, or surgery 3 days to 6 weeks prior to onset of neurologic symptoms. Initial symptoms include numbness, paresthesias, weakness, and pain and may be preceded by vague back or neck pain.