MRCP UK EXAMINATIONS

Detailed explanation-1: -Mononeuritis multiplex is a painful, asymmetrical, asynchronous sensory and motor peripheral neuropathy involving isolated damage to at least 2 separate nerve areas. Multiple nerves in random areas of the body can be affected. As the condition worsens, it becomes less multifocal and more symmetrical.

Detailed explanation-2: -In rare cases, mononeuritis multiplex can be caused by bacterial or viral infection directly in the nerves. For example, mononeuritis multiplex can be linked to HIV infections and hepatitis B infections. Cancer can also cause mononeuritis multiplex, especially if a tumor is interfering with a nerve.

Detailed explanation-3: -Mononeuritis multiplex is actually a group of symptoms rather than its own disease. Its symptoms include numbness, tingling, abnormal sensation, lack of sensation, difficulty to control movement, or an inability to move a part of the body.

Detailed explanation-4: -MNM is most commonly caused by vasculitis, which may be either systemic or isolated to the nerves. Other causes include hypersensitivity reactions to drugs or infections, or direct viral or bacterial infection of nerves. Diagnosis is based on clinical picture and characteristic changes seen on biopsy.