MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A nurse cares for a client with megaloblastic anemia who had a total gastrectomy three years ago. What statement will the nurse include in the client’s teaching regarding the condition?
A
“The condition is likely caused by a vitamin B12 deficiency.”
B
“The condition causes abnormally rigid red blood cells.”
C
“The condition causes abnormally small red blood cells.”
D
“The condition is likely caused by a folate deficiency.”
Explanation: 

Detailed explanation-1: -People who have had a total gastrectomy will need to supplement their diet with regular vitamin B12 injections. Two components necessary for vitamin B12 absorption, gastric acid, and intrinsic factor, are less available or not available with the removal of all or part of the stomach.

Detailed explanation-2: -Background: Vitamin B12 deficiency is a common long-term sequelae after total gastrectomy. Intramuscular injection of vitamin B12 is the only known treatment.

Detailed explanation-3: -Vitamin B12 and vitamin B9 help form red blood cells. Without enough vitamin B12 or vitamin B9, your body produces abnormal cells called megaloblasts. Megaloblasts don’t divide and reproduce like healthy cells, which means there are fewer red blood cells in your bone marrow.

Detailed explanation-4: -Vitamin B12 deficiency causes megaloblastic anemia and neurological symptoms, and is known to develop within 5 or 6 years after total gastrectomy, a delay that reflects the time needed to exhaust cobalamin stores after cobalamin absorption ceases[25].

There is 1 question to complete.