MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A patient has a Mantoux skin test prior to being placed on a biologic medication for the treatment of Crohn’s disease. Which results would determine that the medication may be administered as prescribed by the nurse?
A
0 to 4 mm
B
5 to 6 mm
C
7 to 8 mm
D
9 mm
Explanation: 

Detailed explanation-1: -The test is “positive” if there is a bump of a certain size where the fluid was injected. This means you probably have TB germs in your body. Most people with a positive TB skin test have latent TB infection. To be sure, your doctor will examine you and give you a chest x-ray.

Detailed explanation-2: -The Tuberculin Skin Test (TST) The TST, or Mantoux test, is the commonest test used to screen for latent tuberculosis infection and depends on the intradermal injection of a specified quantity of an internationally standardized purified protein derivative (PPD) of tuberculin.

Detailed explanation-3: -The Mantoux Test (MT) is a classical delayed-type hypersensitivity (DTH) response to the intradermal injection of tuberculin purified protein derivative (PPD). It represents a cutaneous T cell mediated memory recall immune response.

Detailed explanation-4: -The positive skin reaction in the PPD test can occur in: Active TB infection. TB exposure in the past (latent TB infection) BCG vaccination in the past (live attenuated mycobacterial strain) Infection with a variety of non-tuberculosis Mycobacteria.

There is 1 question to complete.