NEUROLOGY
SURGERY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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To prevent this, the body has a thrombolytic (fibrinolytic) mechanism that eventually dissolves clots formed within blood vessels.
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Excessive clotting is equally dangerous, because it can obstruct blood flow to vital tissues.
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An intricate clotting mechanism is activated when necessary to seal any leak in the blood vessels. Excessive clotting is equally dangerous, because it can obstruct blood flow to vital tissues. To prevent this, the body has a thrombolytic (fibrinolytic) mechanism that eventually dissolves clots formed within blood vessels.
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An intricate clotting mechanism is activated when necessary to seal any leak in the blood vessels.
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Detailed explanation-1: -Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The pathophysiology of trauma-induced coagulopathy consists of coagulation activation, hyperfibrino(geno)lysis, and consumption coagulopathy. These pathophysiological mechanisms are the characteristics to DIC with the fibrinolytic phenotype.
Detailed explanation-2: -Indeed, elevation of factor VIII activity seems to be the most robust effect of severe multiple trauma in terms of clotting factor activities. A possible explanation is the known role of factor VIII as an acute phase protein [28].
Detailed explanation-3: -The treatment of trauma-related bleeding starts at the site of the accident with compression, tourniquets, and a pelvic binder to prevent further blood loss, followed by rapid transport to a certified trauma center.
Detailed explanation-4: -Although there are several different mechanisms of injury, trauma can be categorized broadly into three groups: penetrating, blunt, and deceleration trauma. There is a significant overlap in the causes, outcomes, and body’s response to the different injury types.