NEUROLOGY
SURGERY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A patient with chronic kidney disease is identified as having anemia. Which laboratory test results will the nurse likely observe?
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Decreased level of erythropoietin
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Decreased total iron-binding capacity
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Increased mean corpuscular volume
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Increased reticulocyte count
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Explanation:
Detailed explanation-1: -Anemia of CKD tends to primarily involve functional iron deficiency. Traditionally, this is characterized by a TSAT less than 20% and a ferritin level less than 100 ng/mL; however, there is evidence that those cutoffs may not be sensitive to detect iron deficiency.
Detailed explanation-2: -The first recombinant human erythropoietin (Epogen® [epoetin alfa], Amgen) in 1989 (Eschbach et al 1989) significantly improved the clinical management of anemia of CKD, primarily in dialysis patients. By 2005, 99% of in-center hemodialysis patients received ESA treatment for their anemia, as outlined in Table 1.
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