MRCP UK EXAMINATIONS

Detailed explanation-1: -Erythropoietin is a hormone produced by the kidneys. It stimulates the bone marrow to produce more red blood cells (RBCs). Erythropoietin is frequently used to correct anaemia caused by a reduced number of red blood cells or low haemoglobin concentration in cases of chronic renal failure.

Detailed explanation-2: -EPO tells your body to make red blood cells. When you have kidney disease, your kidneys cannot make enough EPO. Low EPO levels cause your red blood cell count to drop and anemia to develop. Most people with kidney disease will develop anemia.

Detailed explanation-3: -Not having enough EPO (a hormone made by your kidneys) is the most common cause of anemia in patients with kidney disease and kidney failure. EPO tells your body to make red blood cells. When your kidneys no longer make enough EPO, treatment with drugs called erythropoiesis-stimulating agents (ESAs) can help.

Detailed explanation-4: -Anemia in people with CKD often has more than one cause. When your kidneys are damaged, they produce less erythropoietin (EPO), a hormone that signals your bone marrow-the spongy tissue inside most of your bones-to make red blood cells.