MRCP UK EXAMINATIONS

Detailed explanation-1: -Hematopoiesis that occurs in your bone marrow is called medullary hematopoiesis. Blood cells get made in your bone marrow and released into your bloodstream. Less often, hematopoiesis takes place in other parts of your body, like your liver and spleen.

Detailed explanation-2: -In adults, hematopoiesis occurs in the bone marrow-the central cavity of your bones. Hematopoiesis starts with hematopoietic stem cells (HSCs), proliferative and multipotent cells that are located in specialized bone marrow regions called ‘niches’.

Detailed explanation-3: -Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood. If a stem cell commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell.

Detailed explanation-4: -After birth, and during early childhood, hematopoiesis occurs in the red marrow of the bone. With age, hematopoiesis becomes restricted to the skull, sternum, ribs, vertebrae, and pelvis.

Detailed explanation-5: -Hematopoiesis is responsible for the formation of all blood cells from hematopoietic stem cells (HSC) in the bone marrow (BM). It is a highly regulated process, in order to adapt its cellular output to changing body requirements.