MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Describe the two main types of emphysema.
A
panlobular (panacinar) type of emphysema, there is destruction of the respiratory bronchiole, alveolar duct, and alveolus.
B
centrilobular (centroacinar) form, pathologic changes take place mainly in the center of the secondary lobule, preserving the peripheral portions of the acinus (i.e., the terminal airway unit where gas exchange occurs).
C
enlarged submucosal glands (proximal airways
D
inflammation and air way narrowing (peripheral airways), and narrowing of the airway lumen.
Explanation: 

Detailed explanation-1: -There are three types of emphysema; centriacinar, panacinar, paraseptal. See image 1. Centriacinar emphysema affects the alveoli and airways in the central acinus, destroying the alveoli in the walls of the respiratory bronchioles and alveolar ducts . Panacinar emphysema affects the whole acinus .

Detailed explanation-2: -Centrilobular emphysema is a form of chronic lung disease. This form of emphysema affects the upper lobes of the lungs and is common in people who smoke. Centrilobular emphysema is also called centriacinar emphysema. It is most common in people over the age of 50 with a history of smoking.

Detailed explanation-3: -Centriacinar emphysema is the most common type of pulmonary emphysema mainly localized to the proximal respiratory bronchioles with focal destruction and predominantly found in the upper lung zones. The surrounding lung parenchyma is usually normal with untouched distal alveolar ducts and sacs.

Detailed explanation-4: -Centriacinar – Begins in the respiratory bronchioles and spreads mainly in the upper half of the lungs. Panacinar – Commonly resides in the lower half of the lungs and destroys the tissue of the air sacs, causing a distinctive, uniform enlargement of air spaces. More items

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