MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hodgkin lymphoma
A
Proliferative disorder of the myeloid stem cells
B
Stem cell disease within the bone marrow
C
Unicentric in origin and is initiated in a single node
D
Heterogeneous group of cancers that originate from the neoplastic growth of lymphoid tissue
Explanation: 

Detailed explanation-1: -Although Hodgkin lymphoma can start almost anywhere, most often it starts in lymph nodes in the upper part of the body. The most common sites are in the chest, neck, or under the arms. Hodgkin lymphoma most often spreads through the lymph vessels from lymph node to lymph node.

Detailed explanation-2: -Nodular lymphocyte–predominant Hodgkin’s disease is also derived from a B cell, as indicated by clonal VDJ rearrangements of the IgH chain locus in the malignant lymphocytic and histiocytic (L&H) cells of this disease 13 14 15.

Detailed explanation-3: -Hodgkin lymphoma can start anywhere in the lymphatic system. It can develop in more than one place in the body at the same time. The most common place for it to be noticed is in the lymph nodes in the neck. But it can start in any of the lymph nodes in the body.

There is 1 question to complete.