MRCP UK EXAMINATIONS

Detailed explanation-1: -In both circular and longitudinal smooth muscle layers, GABA increased the frequency, and decreased the amplitude of the contractions.

Detailed explanation-2: -What is gamma-aminobutyric acid (GABA)? Gamma-aminobutyric acid (GABA) is a neurotransmitter, a chemical messenger in your brain. It slows down your brain by blocking specific signals in your central nervous system (your brain and spinal cord). GABA is known for producing a calming effect.

Detailed explanation-3: -GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect.