MRCP UK EXAMINATIONS

Detailed explanation-1: -Myelodysplastic syndrome (MDS) is a heterogeneous group of hematologic neoplasms classically described as a clonal disorder of hematopoietic stem cells leading to dysplasia and ineffective hematopoiesis in the bone marrow. Some patients with MDS may have a transformation into acute myeloid leukemia (AML).

Detailed explanation-2: -Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly formed or don’t work properly. Myelodysplastic syndromes result from something amiss in the spongy material inside your bones where blood cells are made (bone marrow).

Detailed explanation-3: -Myelodysplastic syndromes (MDS) are a type of rare blood cancer where you don’t have enough healthy blood cells. It’s also known as myelodysplasia. There are many different types of MDS. Some types can stay mild for years and others are more serious.

Detailed explanation-4: -This syndrome is caused by inherited changes in the RUNX1 gene. Normally, this gene helps control the development of blood cells. Changes in this gene can lead to blood cells not maturing like they normally would, which can increase the risk of developing MDS.