MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Non-Hodgkin lymphoma
A
Proliferative disorder of the myeloid stem cells
B
Stem cell disease within the bone marrow
C
Unicentric in origin and is initiated in a single node
D
Heterogeneous group of cancers that originate from the neoplastic growth of lymphoid tissue
Explanation: 

Detailed explanation-1: -Non-Hodgkin lymphoma is a group of malignant neoplasms originating from the lymphoid tissues, mainly the lymph nodes. These tumors may result due to chromosomal translocation, various toxins, infections, and chronic inflammation.

Detailed explanation-2: -Non-Hodgkin’s lymphoma most often begins in the: B cells. B cells are a type of lymphocyte that fights infection by producing antibodies to neutralize foreign invaders. Most non-Hodgkin’s lymphoma arises from B cells.

Detailed explanation-3: -Non-Hodgkin lymphomas are a heterogeneous group of disorders involving malignant monoclonal proliferation of lymphoid cells in lymphoreticular sites, including lymph nodes, bone marrow, the spleen, the liver, and the gastrointestinal tract. Presenting symptoms usually include peripheral lymphadenopathy.

Detailed explanation-4: -People who have had non-Hodgkin lymphoma (NHL) can get any type of second cancer, but they have an increased risk of certain cancers, including: Melanoma skin cancer. Lung cancer. Kidney cancer.

Detailed explanation-5: -Diffuse large B-cell lymphoma (DLBCL): The most common type of non-Hodgkin lymphoma in the United States, DLBCL accounts for about 30 percent of all cases. It is most often diagnosed in older adults. DLBCL is aggressive and may spread quickly.

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