MRCP UK EXAMINATIONS

Detailed explanation-1: -Plasma contains 91% to 92% of water and 8% to 9% of solids. It mainly comprises of: Coagulants, mainly fibrinogen, aid in blood clotting. Plasma proteins, such as albumin and globulin, that help maintain the colloidal osmotic pressure at about 25 mmHg.

Detailed explanation-2: -More than 90 percent of plasma is water. The remainder is mostly plasma proteins-mainly albumin, globulins, and fibrinogen-and other dissolved solutes such as glucose, lipids, electrolytes, and dissolved gases.

Detailed explanation-3: -Globulins are a group of proteins in your blood. They are made in your liver by your immune system. Globulins play an important role in liver function, blood clotting, and fighting infection. There are different types of globulins called alpha, beta, and gamma globulins.

Detailed explanation-4: -The globulin fraction includes hundreds of serum proteins including carrier proteins, enzymes, complement, and immunoglobulins. Most of these are synthesized in the liver, although the immunoglobulins are synthesized by plasma cells.

Detailed explanation-5: -The protein concentration in plasma/serum is approximately 60–80 mg/mL of which about 50–60% are albumins and 40% globulins (10–20% immunoglobulin G, IgG) [7, 8]. The size distribution of blood components ranges from small molecules and ions (< 1 nm) to about 15 m for white blood cells.