Prostaglandins are primary chemical mediators that respond to a stimulus by contracting smooth muscle and increasing capillary permeability. This response causes .....

SURGERY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Prostaglandins are primary chemical mediators that respond to a stimulus by contracting smooth muscle and increasing capillary permeability. This response causes ____

A	the pain and fever seen with inflammatory responses
B	arthritis
C	dermatitis
D	allergy

Explanation:

Detailed explanation-1: -Prostaglandins play a key role in the generation of the inflammatory response. Their biosynthesis is significantly increased in inflamed tissue and they contribute to the development of the cardinal signs of acute inflammation.

Detailed explanation-2: -Cyclopentenone prostaglandins (cyPGs) are biologically active lipid mediators, including PGA2, PGA1, PGJ2, and its metabolites. cyPGs are essential regulators of inflammation, cell proliferation, apoptosis, angiogenesis, cell migration, and stem cell activity.

Detailed explanation-3: -Prostaglandin (PG) is an inflammatory mediator that appears to be important in genesis and maintenance of neuropathic pain.

Detailed explanation-4: -The affected tissue would release prostaglandins to narrow affected blood vessels to try to lessen blood loss. The affected tissue would release prostaglandins that trigger the inflammatory response, causing blood vessels to leak fluid into the tissues (swelling).

There is 1 question to complete.

MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY