MRCP UK EXAMINATIONS

Detailed explanation-1: -In the average adult human, there is roughly 150 mL of CSF circulating at any given moment. The ventricular portion amounts to roughly 17% of the total fluid volume, the rest of which lies in the cisterns and subarachnoid space.

Detailed explanation-2: -Adult CSF volume is estimated to be 150 ml with a distribution of 125 ml within the subarachnoid spaces and 25 ml within the ventricles. CSF is predominantly secreted by the choroid plexus with other sources playing a more poorly defined role, an adult produces between 400 to 600 ml per day.

Detailed explanation-3: -The brain produces roughly 500 mL of cerebrospinal fluid per day, at a rate of about 25 mL an hour. This transcellular fluid is constantly reabsorbed, so that only 125–150 mL is present at any one time. CSF volume is higher on a mL per kg body weight basis in children compared to adults.