Type IlI hypersensitivity reactions involve the binding of antibodies to antigens. List two possible results: ..... and .....

SURGERY

Please wait while the activity loads.
If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled.

If loading fails, click here to try again

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Type IlI hypersensitivity reactions involve the binding of antibodies to antigens. List two possible results: ____ and ____

A	arthritis
B	serum sickness
C	certain types of nephritis
D	some types of bacterial endocarditis.

Explanation:

Detailed explanation-1: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen.

Detailed explanation-2: -Type II or antibody-mediated hypersensitivity In the effector phase, target cells become coated with antibodies, a process termed opsonization, which leads to cellular destruction by three mechanisms: (1) phagocytosis, (2) complement-dependent cytotoxicity (CDC), and (3) ADCC.

Detailed explanation-3: -Immediate hypersensitivity reactions are predominantly mediated by IgE, IgM, and IgG antibodies.

Detailed explanation-4: -In type III hypersensitivity reactions, an abnormal immune response is mediated by the formation of antigen-antibody aggregates called “immune complexes."[1] They can precipitate in various tissues such as skin, joints, vessels, or glomeruli and trigger the classical complement pathway.

There is 1 question to complete.

MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY