MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are the potential long-term complications of therapy for a patient with Hodgkin lymphoma?
A
Second cancers.
B
Fertility issues
C
Infections
D
Thyroid problems
E
Heart disease and stroke
Explanation: 

Detailed explanation-1: -Second cancers. One uncommon but very serious side effect of HL treatment is developing a second type of cancer later on. Fertility issues. Infections. Thyroid problems. Heart disease and stroke. Lung damage. Special concerns in childhood Hodgkin lymphoma survivors. 01-May-2018

Detailed explanation-2: -Radiation dose to the heart valves can increase the risk for clinically significant VHD, especially at doses above 30 Gy. However, for patients with mediastinal involvement treated today with 20 or 30 Gy, the 30-year risk will be increased by only about 1.4%.

Detailed explanation-3: -People who have received doxorubicin-based chemotherapy or radiation therapy to the chest may be at higher risk for developing heart problems, such as heart failure, valvular disease, pericarditis, and rhythm abnormalities.

Detailed explanation-4: -The main treatments for Hodgkin lymphoma are chemotherapy alone, or chemotherapy followed by radiotherapy. Occasionally, chemotherapy may be combined with steroid medicine. Some people also have biological medicines. Surgery isn’t generally used to treat the condition, except for the biopsy used to diagnose it.

Detailed explanation-5: -Skin changes. Risk of a second cancer. Heart problems. Changes in the way your thyroid gland works. Infertility after radiotherapy to the pelvis. Inflammation of the lungs (pneumonitis)

There is 1 question to complete.