NEUROLOGY
SURGERY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The signs and symptoms result from insufficient production of normal blood cells.
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The results will show an excess of immature blast cells, which is the hallmark of the diagnosis.
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he goal of treatment is to obtain remission without excess toxicity and with a rapid hematologic recovery so that additional therapy can be administered if needed.
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Because the illness is unpredictable.
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Detailed explanation-1: -Anemia can manifest with fatigue, weakness, pallor, malaise, dyspnea on exertion, tachycardia, and exertional chest pain. Thrombocytopenia can cause mucosal bleeding, easy bruising, petechiae/purpura, epistaxis, bleeding gums, and heavy menstrual bleeding.
Detailed explanation-2: -Many signs and symptoms of AML are the result of a shortage of normal blood cells, which happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets.
Detailed explanation-3: -Most patients with AML present with anemia (median hemoglobin 8 g%), thrombocytopenia (median platelet count 40, 000–50, 000/L), and leukocytosis (median white blood cell count 10, 000–20, 000/L). The red blood cell morphology is usually relatively normal.
Detailed explanation-4: -In AML, the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets. When the abnormal cells crowd out the healthy cells, it can lead to infection, anemia, and easy bleeding. The abnormal cells can also spread outside the blood to other parts of the body.
Detailed explanation-5: -Fever. Bone pain. Lethargy and fatigue. Shortness of breath. Pale skin. Frequent infections. Easy bruising. Unusual bleeding, such as frequent nosebleeds and bleeding from the gums. 21-Sept-2022