MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the goal of treatment in acute lymphocytic leukemia (ALL)?
A
The goal of treatment is to obtain remission without excess toxicity and with a rapid hematologic recovery so that additional therapy can be administered if needed.
B
The results will show an excess of immature blast cells, which is the hallmark of the diagnosis.
C
The signs and symptoms result from insufficient production of normal blood cells.
D
Because the illness is unpredictable.
Explanation: 

Detailed explanation-1: -The treatment of adult ALL usually has two phases. Remission induction therapy: This is the first phase of treatment. The goal is to kill the leukemia cells in the blood and bone marrow. This puts the leukemia into remission. Post-remission therapy: This is the second phase of treatment.

Detailed explanation-2: -The goal is to clear the blood of leukemia cells (blasts) and to reduce the number of blasts in the bone marrow to normal. Consolidation is chemo given after the patient has recovered from induction.

Detailed explanation-3: -Many different drugs and drug combinations can be used as the first treatment for CLL. The options include monoclonal antibodies, targeted drugs, chemotherapy, and different combinations of these. Some of the more commonly used drug treatments include: Ibrutinib (Imbruvica), alone or with rituximab (Rituxan)

Detailed explanation-4: -The goal is to kill as many leukemia cells as possible in your blood and bone marrow to achieve remission. In remission, blood cell counts return to normal levels, no leukemia cells are found in your blood, and all signs and symptoms of the disease disappear. Induction therapy usually lasts four to six weeks.

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