MRCP UK EXAMINATIONS

RESPIRATORY

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
An exacerbation in COPD is:
A
A period of increase/worsening of disease symptoms.
B
A period of stability of symptoms
C
A period of improvement in symptoms
D
A period of deterioration of the lung tissue but the symptoms do not change
Explanation: 

Detailed explanation-1: -An exacerbation of COPD is described as an acute worsening of respiratory symptoms associated with a variable degree of physiological deterioration.

Detailed explanation-2: -Exacerbation: A worsening. In medicine, exacerbation may refer to an increase in the severity of a disease or its signs and symptoms. For example, an exacerbation of asthma might occur as a serious effect of air pollution, leading to shortness of breath.

Detailed explanation-3: -Exacerbations of COPD are thought to be caused by complex interactions between the host, bacteria, viruses, and environmental pollution. These factors increase the inflammatory burden in the lower airways, overwhelming the protective anti-inflammatory defences leading to tissue damage.

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