MRCP UK EXAMINATIONS

RESPIRATORY

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Regarding the drug treatment of COPD, which of the following is NOT?
A
Short-acting inhaled
B
LAMA (tiotropium) is more effective than LABA in reducing the rate of exacerbations
C
Aminophylline is recommended for routine use to improve lung function and exercise tolerance
D
Eosinophil > 300, may be better with ICS
Explanation: 

Detailed explanation-1: -Antibiotics. Respiratory infections, such as acute bronchitis, pneumonia and influenza, can aggravate COPD symptoms. Antibiotics help treat episodes of worsening COPD, but they aren’t generally recommended for prevention.

Detailed explanation-2: -Background: Intravenous aminophylline is commonly used in the treatment of exacerbations of chronic obstructive pulmonary disease (COPD), despite limited evidence for its efficacy and known risks of toxicity.

Detailed explanation-3: -Examples of long-lasting beta2-agonists are salmeterol, formoterol, indacaterol, and vilanterol. Long-lasting beta2-agonists are taken every 12 to 24 hours, providing more convenient treatment of COPD than short-acting drugs that are usually used as “rescue medications” to relieve sudden onset of shortness of breath.

Detailed explanation-4: -beta-2 agonist inhalers – such as salmeterol, formoterol and indacaterol. antimuscarinic inhalers – such as tiotropium, glycopyronium and aclidinium.

There is 1 question to complete.