MRCP UK EXAMINATIONS

RESPIRATORY

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is incorrect for the initial setting of mechanical ventilation for patients with chronic obstructive pulmonary disease?
A
Tidal volume:6-8 ml/kg body weight
B
PEEP is set at 80% of auto-PEEP
C
Inhalation time:0.6-1.2 seconds
D
Breathing frequency:8-16 breaths/minute
Explanation: 

Detailed explanation-1: -Pulmonary barotrauma is a frequent complication of PEEP therapy. Pneumothorax, pneumomediastinum, and interstitial emphysema may lead to rapid deterioration of a patient maintained on mechanical ventilation with an already compromised respiratory status.

Detailed explanation-2: -Initial ventilator settings are recommended like that; TV: 6–10 ml/kg, FiO2: 1.0, RR: 10–14 breaths/minute, no PEEP, inspiratory flow rate: 80–100 liter/minute with square waveform [1, 2, 4].

Detailed explanation-3: -The majority of patients with acute respiratory failure due to acute exacerbations of COPD (AECOPD) should undergo a trial of noninvasive mechanical ventilation (NIV) because intubation can be successfully avoided and mortality reduced with this intervention [1-7].

Detailed explanation-4: -Initial settings for ventilation may be summarized as follows: Assist-control mode. Tidal volume set depending on lung status-Normal = 12 mL/kg ideal body weight; COPD = 10 mL/kg ideal body weight; ARDS = 6-8 mL/kg ideal body weight. Rate of 10-12 breaths per minute.

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