MRCP UK EXAMINATIONS

Detailed explanation-1: -It was during a routine autopsy on a child who was thought to have had celiac disease that Dr. Andersen noticed a lesion in the pancreas. Intrigued, she searched autopsy records and medical literature, and discovered a discrete disease pattern. She called this pattern cystic fibrosis.

Detailed explanation-2: -Caring for anyone with a long-term disease-especially if that person is your child-is stressful. Parents of children with cystic fibrosis are more likely to experience anxiety, depression, or both compared to parents in general.

Detailed explanation-3: -Cystic fibrosis (CF) was first recognized as a separate disease entity in 1938 when autopsy studies of malnourished infants distinguished a disease of mucus plugging of the glandular ducts, termed “cystic fibrosis of the pancreas, ‘’ from others with celiac syndrome (1).

Detailed explanation-4: -The CFTR gene itself was discovered in 1989 by a team of researchers led by Dr. Lap-Chee Tsui in Canada. It was, in fact, the first disease-causing gene to be identified in any disease, so this was one of the most significant breakthroughs in human genetics.