MRCP UK EXAMINATIONS

RESPIRATORY

CYSTIC FIBROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
If both parents are hybrid for CF then what are the possible genotypes???
A
Cc
B
CC
C
cc
D
Ca
Explanation: 

Detailed explanation-1: -Sickle cell anemia refers to an abnormal homozygote genotype (SS or CC), whereas sickle cell trait refers to heterozygote genotype AS or AC inducing mild disease.

Detailed explanation-2: -The genotype of the carrier is Ff (one dominant non-disease gene, F, and one recessive, CF gene, f).

Detailed explanation-3: -Incomplete Dominance Curly hair type (CC) is dominant to straight hair type (cc). An individual who is heterozygous for this trait will have wavy hair (Cc).

Detailed explanation-4: -Heterozygous means one of each allele in the genotype (ex: Cc).

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