MRCP UK EXAMINATIONS

RESPIRATORY

CYSTIC FIBROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Patients with cystic fibrosis will have what type of secretions (sweat, tears, saliva, mucous)?
A
Thin
B
Thick, Sticky
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -In people with cystic fibrosis, the secretions are abnormally thick and sticky, so that they don’t move as easily. Instead of acting as lubricants, these thicker secretions may clog tubes, ducts and passageways throughout the body. Cystic fibrosis also causes increased salt in sweat on the skin.

Detailed explanation-2: -The volume and pH of the saliva were lower for CF patients when compared with healthy subjects.

Detailed explanation-3: -CF mucus is often described as more solid and having a “flake” form. In addition, it has a higher concentration of proteins called mucins. Mucins make up the main component of mucus and are responsible for the gel-consistency of mucus. Non-CF mucus is composed mainly by two types of mucins: MUC5AC and MC5B.

There is 1 question to complete.