MRCP UK EXAMINATIONS

Detailed explanation-1: -There are about 30, 000 people with cystic fibrosis in the United States and approximately 70, 000 people worldwide. Approximately 1 in 30 Americans is a carrier.

Detailed explanation-2: -There are close to 40, 000 children and adults living with cystic fibrosis in the United States (and an estimated 105, 000 people have been diagnosed with CF across 94 countries). Approximately 1, 000 new cases of CF are diagnosed each year. More than 75 percent of people with CF are diagnosed by age 2.

Detailed explanation-3: -Caring for anyone with a long-term disease-especially if that person is your child-is stressful. Parents of children with cystic fibrosis are more likely to experience anxiety, depression, or both compared to parents in general.

Detailed explanation-4: -In the U.S., one in every 31 carries a mutation of the CF gene. Called the cystic fibrosis transmembrane conductance regulator (CFTR) gene, this mutation prevents the CFTR protein from working properly.

Detailed explanation-5: -Among Caucasians, CF occurs in approximately 1 in 3, 000 – 4, 000 live births. Approximately one in 25–30 Caucasians are carriers of a pathogenic mutation of the CFTR gene.