MRCP UK EXAMINATIONS

Detailed explanation-1: -Lung disease, characterized by chronic neutrophilic inflammation, progressive airflow obstruction, and airway bacterial infections, is the major cause of morbidity and mortality in patients with CF [1, 2].

Detailed explanation-2: -Cystic fibrosis can cause sticky mucus to clog the lungs and airways. This can cause: recurring chest infections – these occur because mucus in the lungs is an ideal breeding ground for bacteria. persistent inflammation of the airways, which can cause them to become abnormally widened (bronchiectasis)

Detailed explanation-3: -The most common complication is chronic respiratory infection. Other complications include: Bowel problems, such as gallstones, intestinal blockage, and rectal prolapse.

Detailed explanation-4: -CF causes thick mucus that clogs certain organs, such as the lungs, pancreas, and intestines. This may cause malnutrition, poor growth, frequent respiratory infections, breathing problems, and chronic lung disease. There is no cure for CF.